The Barcelona Institute for Global Health (ISGlobal) is a cutting-edge institute addressing global public health challenges through research, translation into policy and education. ISGlobal has a broad portfolio in communicable and non-communicable diseases including environmental and climate determinants, and applies a multidisciplinary scientific approach ranging from the molecular to the population level. Research is organized in the following main areas: Malaria and Neglected Parasitic Diseases; Global Viral and Bacterial Infections; Maternal, Child and Reproductive Health; Climate, Air Pollution, Nature and Urban Health; Environment and Health over the Lifecourse. ISGlobal is accredited with the Severo Ochoa distinction (received the first accreditation in 2019 and renewed it in 2024), a seal of excellence of the Spanish Science Ministry.

What We Are Looking for:
In the framework of our Centre for Excellence Severo Ochoa Programme (CEX2023-001290-S), ISGlobal is seeking a postdoctoral scientist with advanced expertise in single-cell biology who is interested in taking over a senior technician position to boost the implementation of different types of single-cell technologies at ISGlobal. The overall goal of this position is to provide support to ISGlobal scientists in establishing optimized pipelines for different single-cell techniques, including experimental and bioinformatic analysis pipelines.

The project
As part of the newly awarded Severo Ochoa grant, ISGlobal aims to build capacity on single-cell omics technologies, including single-cell genomics, epigenomics, transcriptomics, and proteomics. This will be used to enhance our capacity to investigate key biological questions, using microbial and human samples from in vitro cultures, in vivo models and epidemiological studies. The development of innovative single-cell omics technologies will allow fostering internationally competitive omics-related infectious diseases (IDs) research at ISGlobal.
Thus far, ISGlobal researchers have used multi-omic approaches to study the human host, pathogens and microbiota for multiple IDs. This was performed in the context of omics-level surveillance and of basic research on host-parasite interactions and immunology. It resulted in the generation of knowledge such as the identification of fingerprints for a wide range of microorganisms, characterisation of silent reservoirs or predictors of vaccine efficacy. This SO action will allow pushing the scope and depth of omics work to frontier research, by dissecting the molecules and processes involved in disease at the cellular level.

This position will be supported by funding from the “Centro de Excelencia Severo Ochoa 2024-2028” Program (CEX 2023-0001290-S) from the Spanish Ministry of Science and Innovation, and the Spanish Research State Agency (MCIN/AEI/10.13039/501100011033).