IRB Barcelona seeks a highly motivated Laboratory Technician to join the Drug Screening Platform at IRB Barcelona.

At IRB Barcelona, we have set up a screening platform with state-of-the-art technology, which allows HTS and provides support for Hit to Lead and Lead Optimisation projects in an efficient and automated way.

At the Drug Screening Platform (DSP), we support Chemical Biology and Drug Discovery projects. Our expert team provides tailored experimental support for a wide range of targets and technologies during the Candidate Discovery phase, from High-Throughput Screening (HTS) to Lead Optimisation.

Currently, we are expanding our facility in order to support the scientific community and move the science a step forward to the discovery of new medicines.

This contract is financed by the project "Drug-screening platform and drug-target interaction analyses", within the framework of the Complementary Plan for Biotechnology Applied to Health. From the Recovery, Transformation and Resilience Plan. Funded by the EU - Next Generation EU, by which establishes a European Union Recovery Instrument to support the recovery after the COVID-19 crisis.

DUTIES:

Assay development (Cellular and biochemical assays)
High Throughput Screening (Cellular and biochemical assays) execution in 384 format and support to H2l and LO activities.
Use of automated screening platforms at user level.
Support compound management activities.
Perform cell culture activities.
Result analysis and result reporting to DSP staff.


EXPERIENCE, KNOWLEDGE, SKILLS:

Must Have – Required:

- Experience:
FPII (Professional Training) or a degree on biomedical field
Experience working in Tissue Culture
Experience in biochemical and cell biology techniques ideally in 96/384 well formats
- Skills:
Good Planning skills
Detail-oriented
Well organized
Clear sense of accountability
Teamwork skills
Customer orientation
Strong initiative and innovation abilities
Ability to learn tasks quickly
Enthusiasm and self-motivated individual with the ability to work independently or with minimal supervision.


Desirable:

- Experience:
More than 3 years in drug discovery in pharma/biotech/academic research.
Experience with assay development, High Throughput Screening (HTS) and compound profiling for both, biochemical and cellular assays.
Familiar with a wide range of targets (enzymes, PPis, GPCRs etc) and technologies (Alpha, HTRF, FP, luminescence, etc).
Familiar with HTS sample processing, data generation, data interpretation and data reporting.
Familiar with HTS equipment (Echo650, multidrop, pipettors, readers, workstations such as CellExplorer etc)
- Knowledge: on drug discovery processes, screening equipment and technologies and a wide range of protein targets, and on how to address the assay development for each one.


WORKING CONDITIONS & ENTITLEMENTS:

Working conditions: Employed in compliance with Spanish legislation and regulations under a full-time contract. Employees receive the benefits of the Spanish Social Security system covering sickness, maternity/paternity leaves and injuries at work.
Estimated annual gross salary: Salary commensurate with experience and qualifications.
International environment: The opportunity to join a prestigious, diverse and inclusive international research institution and to become a member of an established research group.
Benefits: Continuous training in a high-quality environment with unique professional career opportunities.