Dr. Alejandro Couce’s group has used experimental evolution to predict how a gene that destroys a large family of antibiotics can expand its destructive repertoire. The work provides clues about its ability to jump between superbugs and offers a practical roadmap for their surveillance and treatment.Dr. Alejandro Couce’s group has used experimental evolution to predict how a gene that destroys a large family of antibiotics can expand its destructive repertoire. The work provides clues about its ability to jump between superbugs and offers a practical roadmap for their surveillance and treatment.