We are currently accepting applications for the above mentioned position. This is a unique opportunity for highly motivated students recently graduated from the University in Physics or related fields to gain research experience in one of DIPC’s high-profile research teams.

The role
We are looking for a highly motivated student recently graduated or finishing a Master in Physics, Chemistry, or related fields interested in performing a PhD at the X-rays for Inorganic Biochemistry Laboratory (XIBL) of the Donostia International Physics Center (DIPC).

X-ray techniques can provide chemical information with precise spatial resolution to understand the behaviour of therapeutic or diagnostic agents inside patients or cells. Still, biological organisms are not static entities and currently it is not feasible to use X-rays at will on biological samples, as they cause extensive damage to tissues, cells and biomolecules during irradiation. Therefore, dynamic information cannot be acquired on intact samples. The candidate will develop new approaches for the analysis of biologically relevant samples with X-rays imaging or spectroscopic techniques that lays beyond the current state-of-the-art methods using static-by-nature conditions.

Depending on the student’s profile, the project will focus on:

Using continuous flow microfluidic setups to reduce beam damage and achieve temporal resolution during the acquisition of meaningful X-ray spectra (i.e. absorption or scattering) on biological fluids.
Use homogeneous cell populations generated by synchronisation of the cultures to reduce cell-to-cell variability and improve the significance of X-ray microscopy results during the study of dynamic cellular processes.

Desired background & competences
Previous experience in X-ray imaging or spectroscopy, X-ray or neutron scattering, microfluidics and/or cell culture are particularly welcome, but not essential.

The PhD position will be fully funded and secured, but applications from candidates with strong academic records and willing to apply for competitive funding calls are particularly welcome.