IRB Barcelona is seeking a motivated, conscientious, and enthusiastic scientist to join the Inflammation, Tissue Plasticity & Cancer laboratory (Dr. Direna Alonso-Curbelo) as a Laboratory Technician.

Our lab aims to understand how oncogenic mutations and environmental insults alter normal cellular identity and tissue homeostasis to drive and sustain cancer, with a focus on pancreatic and liver malignancies. To do so, we combine functional genomics tools (CRISPR/Cas9; RNAi), mouse models and organoid/cell culture systems, and (epi)genomic methods including single-cell technologies.

The successful candidate will perform molecular/cellular biology techniques (eg. cloning, DNA/RNA/protein extractions, cell culture, genotyping) and in vivo work (eg. preclinical animal models, rodent survival surgeries, tissue processing) to support projects investigating cell-intrinsic and microenvironmental mechanisms of tumor development and metastasis; and will assist in maintaining the lab’s experimental and organizational pipelines.

The candidate will work in close collaboration with other lab members (a lab manager, PhD students and a postdoc) as well as in an independent manner. The successful candidate will also benefit from the dynamic environment of a growing lab and state-of-the-art infrastructures. Both junior and senior candidates will be considered.

Starting date: early october 2023 or as soon as possible.

This position will be partially covered by this position will be partially covered by the project PID2021-128102OA-I00: “Dissecting and targeting early epigenetic programs in pancreatic cancer (PRE-CAN)”.

The position is for 2 years, with a possibility of extension subject to availability of funding.