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A Semester of Mathematics across Two Continents: Eva Miranda at ETH Zürich, ICBS Beijing, and WAIC Shanghai

In the second half of 2025, Eva Miranda (UPC and CRM) delivered a plenary lecture at the International Congress of Basic Science in Beijing, participated as a panellist at the World Artificial Intelligence Conference in Shanghai, and taught a Nachdiplom Lecture course on singular symplectic manifolds at ETH Zürich. In this article, Miranda reflects on how sustained physical presence at international forums and research stays exposes mathematicians to unfamiliar questions and ways of thinking that routine at home cannot provide.

It was supposed to be half an hour. A brief, almost protocolary meeting at ETH with Stephen Wolfram, the physicist and computer scientist behind Mathematica and a long-standing advocate for the idea that computation underlies physical reality, who was passing through Zürich. Eva Miranda, Full Professor at the Universitat Politècnica de Catalunya (UPC) and affiliated researcher at the Centre de Recerca Matemàtica (CRM), had been invited to say hello. Thirty minutes, perhaps a handshake, perhaps a few words about computation and geometry.

They talked for six and a half hours straight.

“He asked very direct questions, almost Socratic,” Miranda recalls. “‘How do you want to attack this?’ That method, seemingly simple but relentless, triggered a completely new impulse.” The conversation dragged her back into a problem she had been circling for years: the undecidability of the three-body problem. She had been thinking about it before, starting from the Sitnikov problem and possible couplings, but routine had absorbed her attention. Wolfram’s visit broke that gravitational pull.

The encounter happened during Miranda’s three-month appointment as Nachdiplom Lecturer at ETH Zürich, one leg of a 2025 that also took her to Beijing, Shanghai, and Göttingen. For a mathematician whose research connects symplectic geometry with fluid dynamics and theoretical computer science, each destination brought different collisions. But the pattern underneath was always the same, sometimes the work that changes you happens when you leave home.

 

From Beijing to Shanghai, through a different scientific culture

In July, Miranda delivered a lecture at the International Congress of Basic Science (ICBS) in Beijing, the annual gathering initiated by Fields Medallist Shing-Tung Yau. The 2025 edition brought nearly a thousand scholars to the Beijing Institute of Mathematical Sciences and Applications, among them over 400 leading scientists, four Fields medallists, three Nobel laureates, and two Turing Award winners.

Her talk, Chaos by Nature: Trajectories of the Undecidable, traced a line from Hilbert’s early twentieth-century dream of a mathematics where every problem could be solved, through Gödel and Turing’s discovery that some questions resist computation altogether, to the more recent confrontation with classical chaos and its sensitivity to initial conditions. Then it went further. In 2021, Miranda and her collaborators Robert Cardona, Daniel Peralta-Salas, and Francisco Presas proved that fluids governed by Euler’s equations can be used to compute, and that this creates trajectories whose behaviour cannot be predicted by any algorithm. The construction relied on contact geometry, a natural framework for encoding complex dynamics.

The lecture also presented more recent work showing that the Navier-Stokes equations can be Turing complete, a result that answers the original question posed by Fields Medallist Terence Tao that started this whole line of research. The paper has been accepted for publication in PNAS Nexus. From there the lecture moved into newer territory: Topological Kleene Field Theory, a computational model that fuses topology, geometry, and logic, and that unveils structural barriers to prediction not only in fluid dynamics but also in celestial mechanics. The question Miranda left the audience with was pointed: is the universe not merely unpredictable, but, at its core, incomputable?

Eva Miranda at the Smale Institute for Mathematics and Computation, co-organiser of the WAIC 2025 forum on Mathematical Frontiers and Foundational Reconstruction of AI.

 

Days later, she was in Shanghai for the World Artificial Intelligence Conference (WAIC), where she participated as a panellist in the forum on Mathematical Frontiers and Foundational Reconstruction of AI, co-organised by the UNIDT and Smale Institute for Mathematics and Computation. The meeting brought mathematicians, computer scientists, and engineers into conversation about large-scale language model optimisation, adversarial modelling, and the still-uncharted relationship between mathematical foundations and artificial intelligence.

“Changing your environment puts you in front of questions you would never have asked on your own, takes you out of comfort and confronts you with other ways of thinking. And sometimes, as happened to me here, it returns you to fundamental problems with a completely renewed energy.”

“The congresses in China were fascinating,” she says. “What surprised me most was the extraordinary care for the guests and the attention to detail in the organisation, which created a very strong sense of hospitality.” She also noticed a strategic intent. “There was a clear ambition to situate research within a global framework, with a very ambitious discourse oriented toward the future. Compared to Europe or the United States, the tone was perhaps more institutional and projective, but at the same time very dynamic, with an energy and a scale that were truly impressive.”

Asked whether forums like ICBS and WAIC succeed in breaking disciplinary boundaries, Miranda is enthusiastic. “I found it very interesting to observe how these congresses foster a real blend of disciplines, creating spaces where it’s natural for mathematicians, physicists, computer scientists and engineers to talk to each other.” The compartments still exist, she adds. Different languages, different organisational structures. “But precisely for that reason, these forums are so important, they act as catalysts that can trigger unexpected connections.”

 

A semester in Zürich

The Nachdiplom Lectures at ETH are among the more rarefied invitations in mathematics. Hosted by the Forschungsinstitut für Mathematik (FIM), founded by Beno Eckmann in 1964, the series brings two to four mathematicians each semester to deliver a full graduate-level course. A selection committee drawn from ETH’s Department of Mathematics, the FIM, and the Zurich Graduate School of Mathematics chooses lecturers whose work defines the frontier of their field. The archive reads accordingly: Alessio Figalli, Claire Voisin, Wendelin Werner, Stanislav Smirnov, Gigliola Staffilani. Many of the courses have become monographs in the EMS book series Zurich Lectures in Advanced Mathematics.

Miranda taught her course, Singular Symplectic Manifolds, from September to December. The subject is one she has shaped over more than a decade, beginning with her collaboration with Victor Guillemin at MIT. The course explored b-symplectic manifolds, structures that are symplectic everywhere except along a critical hypersurface where the geometry degenerates in a controlled way. These structures show up naturally in celestial mechanics, particularly in the restricted three-body problem, and in the geometry of geodesics on the Lorenz plane.

One of the course’s central threads was the technique of desingularisation, a procedure that associates to a singular symplectic structure a family of smooth ones (in the even-exponent case) or folded symplectic structures (in the odd-exponent case). The procedure unifies several apparently distinct geometries under a single framework. The course also pushed toward the frontier of current research, discussing potential approaches to defining Floer homology for b-symplectic manifolds, a new direction at the interface between symplectic topology and Poisson geometry.

The semester produced tangible research progress. “During these three months we made a decisive advance in understanding the relationship between the Morse theory viewpoint and how to arrive at a Floer homology using spectral geometry,” Miranda says. “This conceptual step, seeing how an analytical structure transforms into a global invariant, is not trivial. It required time, insistence, and many good questions.” The students, she adds, were central to that process: “When you have to explain a complex idea to an attentive group, you have to understand it for real. If it doesn’t survive that filter, it’s no good.”

Ask Miranda what mattered most about the semester, and her answer comes without hesitation.

Eva Miranda at ETH Zürich, where she delivered the Nachdiplom Lecture course “Singular Symplectic Manifolds” from September to December 2025.

“The first and most important thing are the students. A large group, extraordinarily motivated, with a real desire to understand. And this is key, because to learn, and to do research, you need to know how to listen, not start from the assumption that you already know everything.” The group she found in Zürich listened, questioned, insisted. “This changes the way you think.”

The classes grew beyond what had been planned. Problem sessions that were not in the original schedule emerged organically. “They became real discussion spaces, where often a well-formulated question would change the course of an entire session.” During the semester, Miranda proposed open research problems. A couple of articles came out of this work; one is already on the arXiv, co-authored with a student to whom she also supervised a semester paper on billiards. “And that is perhaps the most beautiful thing, the work continues.” As a direct consequence of the course and the seminars she gave in Zürich, two ETH master’s students will come to Barcelona to begin doctoral work under her direction.

The stay consolidated other collaborations too. With Adrien Dawid, she is writing a paper on Hofer metrics on singular manifolds, a line of work that gained momentum from their discussions in Zürich. With Joseph Teichmann from the applied mathematics group, she began exploring how her recently developed Topological Kleene Field Theories might relate to reservoir computing. And with the late Dietmar Salamon, who died suddenly in November 2025, she had discussed ideas connecting Floer homology and Poisson geometry.

 

On being somewhere else

“A long stay lets you build a real intellectual community,” Miranda says. “It’s not just transmitting content, it’s sharing the process: making mistakes, going back, reformulating. Watching how an idea matures with time. This kind of work, slower but much deeper, is impossible from a distance.”

She puts it more personally, too. “Travelling frees and relaxes me. I think that’s when the best facets of myself emerge. Maybe that’s why I’m always going from one place to another. Changing your environment puts you in front of questions you would never have asked on your own, takes you out of comfort and confronts you with other ways of thinking.”

As happens often in research, the body pays for the journey. Her menisci suffered from all the uphill and downhill walking in Zürich. “But the mind advances, goes back, rereads the path, and insists. And it is in this constant movement, demanding but profoundly human, where the ideas that are truly worth it are born.”

From the China conferences in summer to the Nachdiplom through autumn and winter, Miranda kept moving between unfamiliar rooms and unfamiliar questions. That accumulation of contact is the thing. “Sharing spaces, coffees, and informal discussions with people of very different profiles makes disciplinary boundaries dissolve,” Miranda says. “A dynamic that rarely happens without sustained physical presence.”

Two master’s students from Zürich will arrive in Barcelona soon to start their theses. A paper on Hofer metrics is being written. The three-body problem has a new angle of attack. Somewhere in Miranda’s notes, there are questions from ETH students that she has not finished answering yet. None of this would have happened from her office in Barcelona.

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Miranda’s 2025 also included a Gauss Professorship at the University of Göttingen, one of the highest honours bestowed by the Göttingen Academy of Sciences. In an interview recorded in the library of the Mathematics Department, she speaks about research, legacy, the challenges of building a career in mathematics.Watch the full interview.

During her stay in Göttingen, she was also interviewed for Mathematical Culture. Read the interview.

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The post A Semester of Mathematics across Two Continents: Eva Miranda at ETH Zürich, ICBS Beijing, and WAIC Shanghai first appeared on Centre de Recerca Matemàtica.

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CRM welcomes Joost J. Joosten and Domènec Ruiz-Balet as affiliated researchers

Joost J. Joosten and Domènec Ruiz-Balet, both from the Universitat de Barcelona, joined the CRM as affiliated researchers in January 2026. Joosten joins the group in Combinatorics and Mathematics of Computer Science, and Ruiz-Balet the group in Partial Differential Equations.

Joost J. Joosten and Domènec Ruiz-Balet joined the Centre de Recerca Matemàtica as affiliated researchers in January 2026. Joosten joins the group in Combinatorics and Mathematics of Computer Science, and Ruiz-Balet joins the group in Partial Differential Equations.

Joost J. Joosten studied Physics and Mathematics at the University of Amsterdam before turning fully to mathematical logic, the field in which he later completed his PhD at Utrecht University on interpretability logics. Postdoctoral stays in Prague, Utrecht, Amsterdam and Seville followed, along with a period in risk management, before a Ramón y Cajal fellowship brought him to Barcelona, where he joined the Department of Logic, History and Philosophy of Science at the Universitat de Barcelona. He has been a member of the IMUB since 2011 and was elected to the Academia Europaea in 2024. Since 2022, he holds an ICREA Acadèmia stipend. His research spans proof theory, ordinal analysis, philosophical logic, and logic applied to computer science and law.

Domènec Ruiz-Balet is an Assistant Professor at the Universitat de Barcelona. His research focuses on the mathematics of machine learning, particularly on areas at the intersection of partial differential equations and dynamical systems, such as deep neural networks and transformers. He also works on mathematical economics, in particular mean-field games and broader game theory. Last January, he co-organised the workshop Mathematical Foundations of Machine Learning: PDEs, Probability, and Dynamics at the CRM, which brought together researchers connecting machine learning with tools from partial differential equations, dynamical systems and probability.

With their arrival, the CRM’s community of affiliated researchers reaches close to one hundred. The CRM extends a warm welcome to both.

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The post CRM welcomes Joost J. Joosten and Domènec Ruiz-Balet as affiliated researchers first appeared on Centre de Recerca Matemàtica.

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Eugenio Coccia awarded Grand Officer of the Order of Merit of the Italian Republic

The director of the Institut de Física d’Altes Energies (IFAE) receives one of Italy’s highest honours for his scientific and civic contributions

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DESI Completes Planned 3D Map of the Universe and Continues Exploring

The Dark Energy Spectroscopic Instrument has completed its planned five-year mission, mapping more than 47 million galaxies and quasars to create the largest high-resolution 3D map of the universe to date, far exceeding its original target of 34 million objects. The project includes the participation of the Institut de Física d’Altes Energies (IFAE).

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CIMCYC Talks: “Prediction and prediction error”

CIMCYC Talks:
The Master in Cognitive and Behavioral Neuroscience invites to the CIMCYC Talks “Prediction and prediction error” with Prof. Rob Honey from the School of Psychology at Cardiff University.
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CIMCYC Talks: “Prediction and prediction error”

CIMCYC Talks:
The Master in Cognitive and Behavioral Neuroscience invites to the CIMCYC Talks “Prediction and prediction error” with Prof. Rob Honey from the School of Psychology at Cardiff University.
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Mitochondria keep immune cells “ready to respond”

Researchers at the Centro Nacional de Investigaciones Cardiovasculares Carlos III (CNIC) show that active mitochondria maintain dendritic cells, the immune system’s sentinels, in a “ready-to-respond” state, linking cellular metabolism to gene regulation and T-cell activation.

The findings, published in Cell Metabolism, open new avenues to improve vaccines and cancer immunotherapy.

The study was led by David Sancho at CNIC and Stefanie K. Wculek at the Institute for Research in Biomedicine (IRB Barcelona), with key contributions from Ignacio Heras Murillo as first author at CNIC.

Dendritic cells play a central role in immunity: they detect threats and activate T cells to fight infections and tumors. Understanding how these cells are regulated is crucial to both enhance immune responses and counteract their dysfunction in diseases such as cancer.

The study reveals that a specific mitochondrial process, the flow of electrons through the respiratory chain, is essential to keep these cells primed. This challenges the long-standing view that mitochondria play only a minor role during dendritic cell activation.

“Our findings show that mitochondria do much more than produce energy, they keep dendritic cells in a ‘ready’ state, allowing them to respond rapidly to threats such as tumors,” explains David Sancho.

Focusing on a specialized subset known as cDC1, which excels at activating tumor-killing T cells, the researchers used genetically modified mouse models and human dendritic cells to dissect mitochondrial function. Surprisingly, they found that immune readiness does not depend primarily on energy production (ATP), but on maintaining electron flow through the mitochondrial chain.

“What is remarkable is that this process is not about energy production, but about preserving the cell’s internal balance, which directly shapes how genes respond to danger signals,” says Ignacio Heras Murillo.

This electron flow preserves the cell’s internal chemical balance, including redox state and metabolite levels. In collaboration with experts in epigenetics, the team showed that disrupting this balance alters DNA methylation patterns at key regulatory regions, molecular switches that enable rapid gene activation. The enzyme TET2 emerged as a critical player, and its activation, for example with vitamin C, enhanced dendritic cell function in experimental models.

Functionally, impaired electron flow had major consequences: dendritic cells showed reduced activation, diminished migration to lymph nodes, and a weakened ability to stimulate T cells. As a result, anti-tumor immune responses were compromised.

“These results highlight metabolism as a key regulator of immune function and suggest new strategies to boost dendritic cell activity in cancer and other diseases,” adds Stefanie K. Wculek.

Importantly, the researchers demonstrated that restoring electron flow could rescue these defects. By introducing an alternative enzyme (AOX), they reinstated mitochondrial function without increasing energy production, recovering the cells’ ability to activate T cells and control tumor growth in mice.

These findings identify a previously unrecognized “electron flow checkpoint” that governs immune cell readiness. Targeting this metabolic pathway could enhance dendritic cell-based therapies, particularly in cancers where immune activation is impaired.

The study highlights metabolism as a powerful lever to fine-tune immune responses and paves the way for new strategies in immunotherapy and vaccine development.”.

This research was conducted by scientists at the Centro Nacional de Investigaciones Cardiovasculares Carlos III and the Institute for Research in Biomedicine Barcelona.

Este proyecto fue financiado por la Fundación “la Caixa” (ID 100010434), beca INPhINIT código LCF/BQ/IN17/11620074 (I.H.-M.). El trabajo del laboratorio de I.M. fue financiado por Fundación Fero. P.H.-A. cuenta con el apoyo de una ayuda JdC IJC2020-042679-I. El trabajo en el laboratorio de D.S. recibió financiación del CNIC; del Ministerio de Ciencia, Innovación y Universidades (MICIU) mediante los proyectos PID2022-137712OB-I00, PDC2025-165319-I00, CPP2022-009762 y CPP2024-011365; MICIU/AEI/10.13039/501100011033 Agencia Estatal de Investigación; Unión Europea NextGenerationEU/PRTR; Comunidad de Madrid (P2022/BMD-7333 INMUNOVAR-CM); Fundación Científica de la Asociación Española Contra el Cáncer (AECC-PRYGN246642SANC); Worldwide Cancer Research (WWCR-25-0080); Unión Europea ERC-POC-2023-GA-101158245-ImnovAth; acuerdo de investigación con Inmunotek S.L.; Fundación CRIS contra el cáncer (excellence2025_03); y la Fundación “la Caixa” (LCF/PR/HR23/52430012 y LCF/PR/HR22/52420019). El laboratorio de S.K.W. y este trabajo cuentan con el apoyo del IRB Barcelona, la Unión Europea y el programa Horizonte Europa del Consejo Europeo de Investigación (ERC-2023-StG “MyTissue”, proyecto número 101117470), así como de las ayudas RYC2022-036400-I y PID2022-140715OA-I00 de MCIN/AEI/10.13039/501100011033 Agencia Estatal de Investigación, Unión Europea NextGenerationEU/PRTR. El IRB Barcelona recibe financiación institucional del Ministerio de Ciencia e Innovación de España, a través del programa Centros de Excelencia Severo Ochoa, y del programa CERCA/Generalitat de Catalunya. M.A.Z. y J.J.F. fueron financiados por la Fundación “la Caixa” bajo el código de proyecto LCF/PR/HR22/52420011 y por la Fundació “La Marató de TV3” (subvención 202314-31). J.A.E. cuenta con financiación de los proyectos PID2021-1279880B-100, TED2024-158440OB-I00 y PID2021-1279880B-100, financiados por MICIU/AEI/10.13039/501100011033 y la Unión Europea “NextGenerationEU”/Plan de Recuperación, Transformación y Resiliencia/PRTR; CIBERFES (CB16/10/00282); Fundación “la Caixa” (LCF/PR/HR23/52430010); y ERC-2024-ADG (GA 101198761). N.S.C. fue financiado por 5R01CA290678. El CNIC cuenta con financiación del Instituto de Salud Carlos III (ISCIII), del MICIU y de la Fundación Pro CNIC, y es un Centro de Excelencia Severo Ochoa (CEX2020-001041-S financiado por MICIU/AEI/10.13039/501100011033).

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LISA mission’s Science Diagnostics Subsystem successfully passes Preliminary Design Review

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Artistic illustration of the LISA interferometer
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The LISA mission has reached a key milestone in its development. The European Space Agency (ESA) has determined that the preliminary design of one of its subsystems—the Science Diagnostics Subsystem (SDS)—meets all mission requirements. This means ESA has given the green light to proceed to the detailed design phase, which will involve testing the system’s first prototypes.

Researchers from the Institute of Space Studies of Catalonia (IEEC) at the Institute of Space Sciences (ICE-CSIC) are leading the Spanish contribution to this project, providing their expertise to the development of the SDS instrument. The project also counts with the collaboration of the Institute of Cosmos Sciences of the University of Barcelona (ICCUB) and the company Sener
 

ICCUB develops the radiation monitor for LISA 
 

The ICCUB team, led by Daniel Guberman, is developing the radiation monitor, a particle detector designed to measure the ionizing radiation flux affecting the LISA Test Masses—one of the mission’s most critical components. Owing to its unique design and location, the radiation monitor is also expected to contribute to fields such as Space Weather and Solar Physics.  

ICCUB researchers Roger Català and Andrey have led the design and implementation of both the electronics and mechanical systems, while Albert Espiña was responsible for the software and firmware.  

The simulations and experimental validation with prototypes were led by Marina Orta, with contributions from Pierpaolo Loizzo (INFN and visiting research fellow at ICCUB) and Roberta Pillera (INFN), supporting the development and validation of the system. One of the key components of the Radiation Monitor is the BETA ASIC, also developed at ICCUB by a team led by David Gascón. 
 

From concept to validation 


The LISA (Laser Interferometer Space Antenna) mission will consist of three spacecraft separated by 2.5 million kilometres that will form a gravitational wave detector, the first to operate from space. Each of the spacecraft will house a mass in freefall in its interior, which will allow, through laser measurements between them, the detection of the effect of low-frequency gravitational waves (0.1 mHz – 1 Hz). The mission will allow for the study of phenomena such as the merger of massive black holes or compact systems in our galaxy, and will expand our vision of the universe.

The SDS is one of the primary components of the mission’s payload led by Spain. In total, the SDS subsystem will put more than one hundred sensors into orbit to measure temperature, magnetic fields, and radiation. These will monitor environmental fluctuations from both the satellite and the interplanetary environment with extreme precision. Detecting gravitational waves requires measuring incredibly weak forces—on the order of the weight of a single bacterium. Therefore, the SDS’s role in distinguishing the effects of gravitational waves from environmental noise is critical to the mission’s success.

The successfully passed evaluation, called PDR (Preliminary Design Review), is the culmination of a process that formally began at the start of the year. The most decisive moment took place on 25 February, when the team travelled to the European Space Research and Technology Centre (ESTEC), ESA’s technical offices in Noordwijk (Netherlands), to review and resolve the open points regarding this key mission system.

The LISA mission, led by ESA, receives funding from the Ministry of Science, Innovation and Universities of Spain through the Spanish Space Agency (AEE). 

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LISA mission’s Science Diagnostics Subsystem successfully passes Preliminary Design Review

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Diario de doctorado | Del modelo matemático al paper publicado: la primera vez de todo se aprende

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The IAA defines the atmosphere of the exoplanet GJ 1214 b with the most complete study to date

The IAA is leading a study that narrows down the nature of the atmosphere of GJ 1214 b, reinforcing the hypothesis of an envelope rich in heavy elements and covered by clouds or hazes. The work incorporates simulations that anticipate how the next generation of telescopes will allow the detection of key molecules and advance in the characterization of this type of atmosphere.

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The IAA-CSIC achieves close to 5% of the total observation time on the James Webb Space Telescope

The IAA-CSIC has secured 407 hours of observation time on the James Webb Space Telescope in a highly competitive international call for proposals, with two of the ten Large programs, the longest and most scientifically demanding. The five approved projects, including the one with the longest observation time in the call, account for approximately 80% of the total led by Spanish institutions.

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The Confining Flux Tube in AdS

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Josep Maria Codina Seminar Room (5th floor)
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The Confining Flux Tube in AdS

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Josep Maria Codina Seminar Room, 5th floor

Abstract: We recently initiated the study of flux tubes in confining gauge theories placed in a rigid Andi-de Sitter (AdS) background, which serves as an infrared regulator. This setup provides a controlled arena to probe a central question in confinement: how the effective string worldsheet degrees of freedom emerge from the underlying UV gauge theory. Varying the AdS radius from large to small interpolates between a flat-space confining string and a weakly coupled string-like object bound by the AdS gravitational potential. In practice, the flux tube is realized as a Wilson loop inserted at the AdS boundary. In this talk, I will explain what we have learned so far about this setup.

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